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37:00
Creatine, AI Doctors, and Sleep Trackers: Notes from the First Don't Die Podcast
This first episode of the Don't Die podcast is a loose weekly roundtable. Bryan Johnson is joined by Kate Tolo, his co-founder at Don't Die, and Dr. Mike Mallin, his lead physician. Johnson says he ta
28:06
Playing AI LIMIT to the End: The "Evolutionary Experiment" Driven by AI and Parry-Centric Combat Design
This video is a full playthrough to the ending of AI LIMIT, a soulslike sci-fi action game set in a world after the collapse of civilization, narrated by a VOICEROID (Kizuna Akari). As the speaker pro
58:39
Building a Robotics Company in Ohio: Path Robotics and Drive Capital on Midwest Venture, AI, and Manufacturing
This live episode of Manufacturing Happy Hour, recorded in front of a packed room in Columbus, Ohio, asked whether the Midwest can build world-class technology companies, and what that looks like in p
26:40Chronologically 31, "Physically 78": Bryan Johnson Audits Comedian Trevor Wallace's Burnout Routine
Comedian Trevor Wallace came to Bryan Johnson's Don't Die podcast with a problem many ambitious people will recognize. He works long days, runs on caffeine, eats whatever is convenient, and wakes up f
10:23
MrBeast's Plan to Turn Video Views Into Meals in Kenya, Ghana, and the United States
The video rests on one claim: every time someone watches it to the end, money is generated, and that money pays for food for people in need. MrBeast (addressed on camera as Jimmy) tells viewers that t
34:58
Anchoring Live Local News: Michelle Khare's Week at CBS8 San Diego
In this episode of Challenge Accepted, Michelle Khare joins the news team at CBS8 in San Diego to learn what it takes to produce a broadcast seen live by roughly 30,000 viewers. Over a few days she tr
54:22
K Allado-McDowell on Neural Media: How AI Locates Us, and Where It Could Look Instead
At a Long Now Talk at San Francisco's Cowell Theatre in February 2025, artist and technologist K Allado-McDowell set out a framework for understanding the moment we are in with AI. They call it "neura
1:02:58The First Berserker: Khazan Normal Difficulty Playthrough: 16 Boss Fights and the Conclusion of Khazan's Revenge
This is a Let's Play video covering the hardcore action RPG The First Berserker: Khazan from the opening through the ending. The commentator (voiced by A.I.VOICE Kotonoha Akane) follows the protagonis
8:55Bryan Johnson's Five-Day Trip to India and the Cost of Breathing
Bryan Johnson, the American tech entrepreneur known for his anti-aging project, went to India to spread his "Don't Die" message. He ended up focused on something else. This video combines his team's f
53:11Bootstrapping Over Venture Capital: Jim Belosic on Rebuilding American Manufacturing
Much of the talk about reindustrializing the United States centers on industrial policy and venture capital. On Manufacturing Happy Hour, Jim Belosic, CEO of SendCutSend, argued for a slower route: bo
7:55Why Bryan Johnson Stopped Taking Rapamycin, a Drug He Hoped Would Slow His Aging
For about four years, Bryan Johnson has worked with a team of medical professionals to build what he calls "the world's best health protocol." One part of that effort was rapamycin, which he describes
7:03Crossing the Brooklyn Bridge Again: Ahmed Best on Vulnerability and Shared Stories
In this short Long Now talk, actor and Afrofuturist Ahmed Best tells one personal story: walking across the Brooklyn Bridge with his young son, twenty years after he had gone to that same bridge inten
1:02:55Ahmed Best's Formula for Feeling the Future: The Emotional Engine, Einstein, and Godzilla
At the Long Now Foundation's Valentine's Day 2025 event at San Francisco's Herbst Theatre, Ahmed Best argued that the future is not only something to think about. It is something to feel, and to share
1:41:45Dr. Mike Israetel and Bryan Johnson on Steroids, Longevity, AI, and What Is Worth the Risk
Bryan Johnson, who has built his public persona around slowing and reversing biological aging, sits down with Dr. Mike Israetel, a competitive bodybuilder, co-founder of Renaissance Periodization (RP)
13:22Lions, Ice, Death Road, and Snake Island: MrBeast's Tour of the "Five Deadliest Places on Earth"
Jimmy (MrBeast) frames this video around one escalating challenge: he and his friends visit what he calls the five deadliest places on Earth. Each stop is meant to be more dangerous than the one befor
31:41Looking Back at Every Boss Fight in Metroid Dread: From a Depowered Samus to Wiping Out the X Along with the Entire Planet
This video is a playthrough of the side-scrolling exploration action game Metroid Dread all the way to the ending. Commentary voiced by A.I.VOICE's Kotonoha Akane traces the flow of the story, the str
54:58Benjamin Bratton on Planetary Computation: Why Our Technology Has Outrun Our Concepts
Benjamin Bratton, Professor of Philosophy of Technology and Speculative Design at UC San Diego and director of the Antikythera program, gave this talk at the Long Now Foundation in January 2025. His c
25:06Kate Tolo Tries SAINT: A Five-Day Magnetic Brain Stimulation Protocol for Depression
Kate Tolo, co-founder of Blueprint with Bryan Johnson, says she has not been herself for about four years. She had wanted to address her depression for a long time but did not want to start SSRIs. Wit
56:57Michelle Khare Defends a Simulated Murder Trial After One Day of Training
Can someone with no legal background learn enough in a single day to defend a client in a murder trial against an experienced prosecutor? On this episode of Challenge Accepted, Michelle Khare plays de
58:32How Skillwork Borrows the Travel Nursing Model to Close the Skilled Trades Gap
In this episode of Manufacturing Happy Hour, host Chris talks with Brett Elliott, President and CEO of Skillwork, and Tim Raglin, the company's Founding Partner and Chief Operating Officer. Skillwork