Aadeel Akhtar on Building PSYONIC's Ability Hand for Amputees and Robots

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Overview

In a conversation on Manufacturing Happy Hour, host Chris Luecke spoke with Dr. Aadeel Akhtar, founder and CEO of PSYONIC, about how a childhood encounter in Pakistan led to a company that makes bionic hands. The central question running through the interview is how one device can serve two very different users: people with limb differences who need an affordable, advanced prosthesis, and robotics companies that need a capable humanlike hand. Akhtar's position is that the two uses reinforce each other. He also treats accessibility as the company's founding principle, and that shapes how PSYONIC seeks insurance coverage, raises money, and plans manufacturing.

19 min read

What PSYONIC Makes

Asked to describe the company as he would to someone at a conference happy hour, Akhtar said PSYONIC develops "advanced bionic limbs that are accessible for humans and robots." He had an Ability Hand with him and demonstrated it live. In the demo he controlled it with two buttons. He explained that a person missing a hand would control it with their own muscles and nerves, while a robot would control it through AI.

Luecke observed that Akhtar seemed to carry the hand everywhere, both in this interview and on Shark Tank. Akhtar joked that it may have become an extension of his body, and that he notices when it is not in his hand.

A Girl in Pakistan and the Original Plan

Akhtar was born in the Chicago suburbs to parents from Pakistan. At seven, while visiting Pakistan, he met someone missing a limb for the first time. She was his age, missing her right leg, using a tree branch as a crutch, and living on the streets near a bazaar where his family was shopping. He said the encounter affected him deeply: they shared an ethnic heritage but had vastly different lives. That experience led to his plan to become a medical doctor who worked with people with amputations and limb differences and helped fit them with prosthetics.

The plan changed in stages. As a biology undergraduate at Loyola University Chicago, he took his first computer science class and loved coding and building things. He realized a conventional MD career would leave little room for that, so he looked for a way to combine prosthetics and engineering. Nearby, at the hospital then called the Rehabilitation Institute of Chicago and now the Shirley Ryan AbilityLab (which he described as the top rehabilitation hospital in the US for roughly 38 years), researchers were making breakthroughs with powered bionic limbs. Surgeons rewired nerves to different muscles, and patients used those new connections to control a multimillion-dollar hand developed by DARPA, Dean Kamen, and Johns Hopkins. Akhtar said that when he saw this, he knew it was exactly what he wanted to do.

He also saw the problem right away. Those hands were so expensive to develop and build that someone like the girl he met in Pakistan could never afford one. He went on to earn a master's in computer science at Loyola and taught there for a couple of years. He then entered the MD/PhD program at the University of Illinois Urbana-Champaign, where he earned a second master's in electrical and computer engineering and a PhD in neuroscience. By then his plan was to finish the MD/PhD, work at an academic hospital, see patients about one day a week, and spend the rest of his time on research and development.

Ecuador and the Decision to Commercialize

The turning point came in summer 2014. Akhtar's group traveled to Quito, Ecuador, with the Range of Motion Project, a nonprofit that provides prosthetics to people who cannot afford them in the US, Guatemala, and Ecuador. He was midway through his PhD, and the team had started 3D printing its own hands. They brought a very early prototype, internally called "Mark 2." He described it as three times the size of an average adult hand, with wires everywhere, breadboards, and power supplies plugged into the wall.

Their first patient, Juan, had lost his left hand 35 years earlier in a landmine explosion while serving in the Ecuadorian army. After making a pinch with his left hand for the first time in 35 years, he told an international news station that he felt as though a part of him had come back. Akhtar said this was when he realized that if he stayed in academia, the work would end up as a journal paper. If everyone was to feel what Juan felt, the technology had to be commercialized. That, he said, is how PSYONIC was born.

Why He Stayed the Course

Luecke asked whether, over a path longer than a decade, Akhtar had ever considered a completely different direction. Akhtar said the goal never changed; only the route was roundabout. It went from MD, to MD/PhD, to an engineering PhD, to a neuroscience PhD, and then to a startup, which was never part of the plan.

The hardest choice was whether to finish medical school while running PSYONIC or to move the company to San Diego and go all in. He described a dinner with his first-year physiology professor, Dr. Kash Ahmed, who told him that his impact as a physician would be important but local to wherever he practiced, while PSYONIC could have global impact. Akhtar said that thinking about the greatest possible benefit kept him grounded. That meant reaching millions of people with limb differences and, eventually, the many companies using robots on manufacturing lines and in homes. In his view, the best way to achieve that is a startup that grows into a large, mature company.

Why San Diego

Luecke noted that medical robotics companies are usually associated with places like Boston. Akhtar pointed to San Diego's medtech and biotech hub, including orthopedic companies such as NuVasive, Globus, and SeaSpine, along with accelerator programs and biotech coming out of UC San Diego.

A key reason is PSYONIC's clinical research partners: Dr. James Flint at the Naval hospital and Dr. Kate Hinchcliffe at UCSD, who are working on the next generation of bionic limbs. Akhtar framed the goal as a broader regional strategy. The military hospital, UCSD, and the Challenged Athletes Foundation are local. The entertainment industry is about two and a half hours north in LA, and potential manufacturing is about 40 minutes south in Tijuana. He wants to bring those resources together and make San Diego "the bionics capital of the world," and said the company is well on its way.

How the Hand Attaches Today, and What Comes Next

Akhtar explained the current setup using a socket that lights up in response to muscle sensors. The user places their residual limb inside the socket, and two muscle sensors on either side detect muscle activity. The lights respond faster when the user flexes harder and slower when they flex less, and the hand responds the same way.

He listed the drawbacks of this approach. The sensors sit outside the body, which he compared to "wearing a shoe over your arm." It gets uncomfortable and sweaty, and under fluorescent lights, 60 Hz electrical noise interferes with the signals. Control is also indirect. Users select pre-programmed grips and cycle through them. He demonstrated a power grip, then slid the thumb over for a thumbs-up, then made a pinch. He said this works but is not the most natural way to control a hand.

The next generation aims to connect the hand the way a natural hand is connected. With Dr. Flint, PSYONIC is working on a titanium implant that goes directly into the bone and exits the body, so the hand can attach to it. With Dr. Hinchcliffe, fine microwire electrodes are implanted directly into nerves and muscles and routed out through a port at the end of the titanium implant. The hand would then be connected to the forearm's bones, muscles, and nerves. The goal is individual finger control instead of cycling through preset grips. Akhtar said that when clinical trials happen, they hope to have their first patients playing piano or typing on a keyboard again. He presented this as a hope for future trials, not a result achieved so far.

A Remote Demo from Milwaukee

To illustrate individual finger control, Akhtar let Luecke control the hand in San Diego from Milwaukee. Luecke held his hand up to the camera. Once it was recognized, the Ability Hand mirrored his fingers as he bent them. The connection briefly dropped when his hand left the frame. After it reconnected, the hand made a peace sign and a thumbs-up. Akhtar said it was one of the first times they had done a demo like this on air, and that it shows the kind of individual finger control the next-generation devices are aiming for.

Accessibility as a Design Requirement

Akhtar called accessibility one of PSYONIC's core tenets and "basically the lifeblood" of the company. From the beginning, a design goal was getting the hand covered by Medicare, because other insurers usually follow Medicare's lead. He said they achieved this, which expanded access from the roughly 10% of patients who could afford the hand to about 75% of Americans, for what he called the most advanced bionic hand on the market.

He said that still leaves about 25% who are uninsured, on Medicaid, or underinsured. It also leaves the 80% of amputees who live in developing nations, of whom fewer than 3% can afford an advanced bionic hand, by his figures. To reach them, PSYONIC created the Ability Fund, which partners with nonprofits to raise money for donated hands. Its most recent partner is the Range of Motion Project, the same organization from the Ecuador trip. According to Akhtar, every $25,000 donated covers a bionic hand plus all clinical services in the US, as well as a leg in Guatemala or Ecuador. He said this usually represents $100,000 to $150,000 worth of devices and services.

The first Ability Fund recipient is a San Diego teenager born without a hand. He emailed Akhtar in high school, said he had loved robotics since he was little, and asked to visit. At PSYONIC's offices he controlled a hand on his left side for the first time. Akhtar said the teen would be fitted the following week with a permanent hand to take home and use daily. "This is why we do what we do," Akhtar said.

Crowdfunding and a Mixed Funding Strategy

Luecke asked whether crowdfunding was connected to this community focus. Akhtar said part of the reasoning was that a company built around accessibility should make the company itself accessible. The result he valued most was that people who wear the hand invested in PSYONIC. He said users rarely get that chance, and that they now help make the product they use.

On managing funding from so many sources, Akhtar described a sequence. Government grants from the National Science Foundation and National Institutes of Health grew out of his PhD research and gave the company a natural jump-start when he went full-time. He put NSF grants at about $2.4 million, possibly more now. To bring the product to market, PSYONIC raised a pre-seed round from angel investors and a few VCs. Then, he said, the company closed a round through StartEngine crowdfunding last year. He called it the seed round at first and later the pre-seed round, and said it raised over $4 million. He explained that the choice was driven by market conditions. Two years earlier had been, in his words, the worst time to raise money from VCs, so they looked for alternatives. He now wants sales to fund further growth.

Scaling Manufacturing When Demand Exceeds Supply

Luecke noted that demand for the hand currently exceeds production and asked how Akhtar balances the big vision with the unglamorous work of running a business. Akhtar credited a tight-knit team. When they moved to San Diego about two and a half years earlier there were seven people; now there are about 35. Everyone sees each other daily and stays aligned.

He said the top priority right now is increasing production. The team is making design changes to simplify design for manufacturing (DFM), and it is on track to quintuple production compared with last year. They are also designing a new version of the hand intended to eventually be made in the tens of thousands per year in a processing plant. He described this as being on the horizon, not in place yet. To carry it out, PSYONIC has hired experienced people locally, including from NuVasive, who have built full manufacturing lines and managed the handoff from engineering to manufacturing. As robotics companies ask for more hands, Akhtar said the company is still keeping ahead of humanoid robot demand, and that as long as it stays ahead, it will be fine.

One Hand for Humans and Robots

Luecke asked how a young company balances two such different markets. Akhtar said robots have historically been specialized for specific tasks and used grippers or pincers instead of humanlike hands. With the AI boom, he has seen rapid growth in the humanoid form factor. His reasoning is that factory jobs are designed for humans, so a robot doing human tasks should use a device optimized for human tasks.

The Ability Hand is self-contained, with all motors and electronics inside. For human users, it attaches with a specific connector. For robots, that connector is swapped for a bolt circle that mounts on arms such as KUKA or UR5, on Apptronik's humanoid robot, or on NASA's Valkyrie humanoid. The internals are the same in both versions.

He illustrated how the two uses feed each other with a story from NASA about a year and a half earlier. Valkyrie was using PSYONIC's hand, and engineers were struggling with a task one might find on the International Space Station: operating a zipper on a wall. PSYONIC's user experience specialist, Anukica Berlin, who wears an Ability Hand, walked up and did it easily. According to Akhtar, the NASA engineers said they hadn't thought of using the hand that way. His conclusion is that human users effectively serve as training sets for robot operators and show the best way to do tasks. He added that tutorial videos made for human users, such as cooking or doing laundry with an Ability Hand, can translate readily to humanoid robots doing the same tasks.

The Technologies That Made It Possible

Asked which advance made this kind of company feasible, Akhtar gave two answers. Over the past decade, the biggest factor has been microcontrollers getting smaller, cheaper, and more powerful. The hand contains seven ARM Cortex processors. He first said M4, then corrected himself to say he thinks they are now M0, which are even smaller. He said this would have been much harder ten years ago: the parts would have been very expensive, and the hand could not have been made this small.

Looking ahead, he expects software and AI to catch up. Low-power hardware with substantial processing capability should allow more efficient AI algorithms to run on the device itself, at the edge, instead of relying on the large computers once needed to process neural and muscle data. He sees this as the next revolution, and one that will benefit technologies like direct nerve implants. He mentioned neurotech companies building brain-machine interfaces, including Neuralink, Synchron, and Phantom Neuro. In his view, these will combine with the AI push in robotics, and PSYONIC sits at the intersection, with AI as the link between neurotech and robotics. Luecke added that the human side belongs in that mix too.

Behind the Scenes at Shark Tank

Akhtar is the show's first Shark Tank alumnus. He said Shark Tank had not been on his radar because PSYONIC makes a medical device, not a direct-to-consumer product. ABC's producers contacted the company first. PSYONIC already had strong marketing material, including a video of Sergeant Anderson, who later appeared on the show with Akhtar, punching through three wooden boards set on fire to show the hand's durability. While brainstorming on the phone with producers, they proposed a live board-breaking demo, and the producers liked it.

He later learned that about 140,000 people or teams applied for Season 15. Around 100 were filmed and about 60 aired, which he calculated as less than half a percent. He joked that if he had known, he might not have gone through the process. The pitch lasted about 45 minutes and was edited down to about 10. He regretted that one cut segment showed Mark Cuban controlling the hand remotely, just as Luecke had in this interview.

He described the experience as "exhilarating and nerve-wracking." The room felt much bigger than expected: the sharks sat about 20 feet away, and distant cameras made them look closer. Only the first two minutes were scripted, including his opening and Anderson's board-breaking. The rest was about 40 minutes of rapid-fire questions. He compared it to a standard VC pitch: if you know your numbers well, not much is different.

On the drama of Mark Cuban and Robert Herjavec declining, Akhtar noted that those were the two sharks PSYONIC had most wanted. The team had rehearsed scenarios such as every shark saying no or various sharks saying yes. He said some of it was impossible to prepare for, and he did not expect three sharks to team up, let alone those particular three. Much of it was spur of the moment.

For the negotiation, the parallel StartEngine campaign mattered. PSYONIC wanted to hold a firm valuation, which he said was about $50 million at the time and is higher now. The strategy was to keep that valuation and give any additional equity as advisor shares to the sharks who joined. He said this worked well. He also pointed out that the on-air deal is only a starting point, followed by due diligence and further negotiation, and that knowing this took some pressure off.

His biggest takeaway from working with high-profile investors was seeing how much excitement now surrounds the field. He recalled the DARPA Robotics Challenge and Google buying robotics companies about ten years ago, followed by a fading of that hype, and said interest is now "way back up." The intersection of neurotech and robotics in particular is nascent and growing faster than ever, in his view. Having major investors behind it validates work he has wanted to do his whole life.

Closing Advice

Asked for final advice, Akhtar talked about gratitude. He said he is grateful to work in a field he has loved and wanted to work in his entire life, and that this makes 80-hour work weeks manageable because it is his life's work. He also said he is grateful for a supportive family and team. He believes a lens of gratitude has contributed greatly to PSYONIC's success and suggested that many companies would benefit from adopting it.